SHIRAZ: An Automated Histology Image Annotation System for Zebrafish Phenomics

Brian A. Canada, Georgia Thomas, Keith Cheng and James Z. Wang
The Pennsylvania State University, University Park, PA 16802
Abstract:

Histological characterization is used in clinical and research contexts as a highly sensitive method for detecting the morphological features of disease and abnormal gene function. Histology has recently been accepted as a phenotyping method for the forthcoming Zebrafish Phenome Project, a large-scale community effort to characterize the morphological, physiological, and behavioral phenotypes resulting from the mutations in all known genes in the zebrafish genome. In support of this project, we present a novel content-based image retrieval system for the automated annotation of images containing histological abnormalities in the developing eye of the larval zebrafish.


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Citation: Brian A. Canada, Georgia Thomas, Keith Cheng and James Z. Wang, ``SHIRAZ: An Automated Histology Image Annotation System for Zebrafish Phenomics,'' Multimedia Tools and Applications, Special Issue on Hot Research Topics in Multimedia, vol. 51, no. 2, pp. 401-440, 2011.

Copyright 2011 Canada, Thomas, Cheng, and Wang. [Springer-verlag Open Access]

Last Modified: Nov 12, 2010.
© 2010