BIB-VERSION:: CS-TR-v2.0 ID:: STAN//CS-TR-86-1115 ENTRY:: May 01, 1995 ORGANIZATION:: Stanford University, Department of Computer Science TITLE:: The heuristic refinement method for deriving solution structures of proteins TYPE:: Technical Report AUTHOR:: Buchanan, Bruce G. AUTHOR:: Hayes-Roth, Barbara AUTHOR:: Lichtarge, Olivier AUTHOR:: Altman, Russ AUTHOR:: Brinkley, James AUTHOR:: Hewett, Micheal AUTHOR:: Cornelius, Craig AUTHOR:: Duncan, Bruce AUTHOR:: Jardetzky, Oleg DATE:: March 1986 PAGES:: 30 ABSTRACT:: A new method is presented for determining structures of proteins in solution. The method uses constraints inferred from analytic data to successively refine both the locations for parts of the structure and the levels of detail for describing those parts. A computer program, called PROTEAN, which encodes this method, has been partially implemented and was used to derive structures for the lac-repressor headpiece from experimental data. NOTES:: [Adminitrivia V1/Prg/19950501] END:: STAN//CS-TR-86-1115