Shared Knowledge Base
PharmGKB – PharmacoGenetics Knowledge Base starting 2000
“An Ontology for Genetic Information” [Russ Altman]
<pharmgkb.org> based at Stanford, funded by NIGMS
to link existing projects – but open to others.
Phenotype variation --> Genotype variation
Phase 2 metabolizing enzymes – R.Weinshllboum at Mayo Clinic
Asthma -- Weiss (was Jeff Raizin) at Havard Un.
Anti-cancer agents -- Mark Ratain at Un. of Chicago
Membrane Transporters -- Kathleen Giacomini, UCSF
Tomoxifen metabolic activation -- Dave Flockhart at Georgetown Un.
Minority Populations and Privacy – M.Rothstein at Univ of Houston ?
Depression in Mexican-Americans -- J.Licinio at UCLA
Database Tools -- Prakash Nadkarni at Yale Un.