SHIRAZ: An Automated Histology Image Annotation
System for Zebrafish Phenomics
Brian A. Canada, Georgia Thomas, Keith Cheng and James Z. Wang
The Pennsylvania State University, University Park, PA 16802
Histological characterization is used in clinical and research
contexts as a highly sensitive method for detecting the morphological
features of disease and abnormal gene function. Histology has recently
been accepted as a phenotyping method for the forthcoming Zebrafish
Phenome Project, a large-scale community effort to characterize the
morphological, physiological, and behavioral phenotypes resulting from
the mutations in all known genes in the zebrafish genome. In support
of this project, we present a novel content-based image retrieval
system for the automated annotation of images containing histological
abnormalities in the developing eye of the larval zebrafish.
Citation: Brian A. Canada, Georgia Thomas, Keith Cheng and
James Z. Wang, ``SHIRAZ: An Automated Histology Image Annotation
System for Zebrafish Phenomics,'' Multimedia Tools and
Applications, Special Issue on Hot Research Topics in Multimedia,
vol. 51, no. 2, pp. 401-440, 2011.
Copyright 2011 Canada, Thomas, Cheng, and Wang. [Springer-verlag Open Access]
Nov 12, 2010.